Mutations in histone regulator protein linked to rare neurodevelopmental disorder, cancers
Mutations in a histone regulator protein are linked to both a rare neurodevelopmental disorder and to some cancers, according to a study published in the...
Cell Proliferation
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Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension
A gene that is overexpressed in some aggressive cancers also appears to be key to the excessive cell proliferation that thickens the walls of pulmonary...
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Researchers develop a highly efficient method to generate immune cells for cancer therapies
A Ludwig Cancer Research study has devised a highly efficient method to generate large numbers of immune cells specifically engineered to recognize neoantigens-;small fragments of...
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Scientists discover key component of cellular malfunction that contributes to growth of tumors
Scientists have homed in on a crucial step within the sequence of chemical reactions that govern regulation of cell division, proliferation and death, and whose...
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Role of SARS-CoV-2 infection biomarkers in HIV replication
The concentration of the proteins S100A8 and S100A9 in serum increases during an inflammatory response. Patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...
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Study highlights the critical role of junk DNA in mammalian development
Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our...
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Impact of BRCA1 mRNA expression on survival of patients breast and colorectal cancer
Oncotarget published “Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients”...
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Critical function of IL-7 in diagnosis, prognosis, and treatment of COVID-19 patients
Interleukin (IL) 7 is essential for the development and function of T-cells. IL-7 binds to the IL-7 receptor (IL-7R), which is a heterodimer structure comprised...