Role of cGAS-STING in SARS-CoV-2 infection
Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that led to the coronavirus disease 2019 (COVID-19) pandemic can cause various clinical presentations ranging...
Cytokines
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Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease
In a preprint version of a study posted on medRxiv*, researchers investigated the longevity and intensity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine...
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COVID-19 may affect a group of biochemical reactions called one-carbon metabolism
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the ongoing pandemic of coronavirus disease 2019 (COVID-19). The SARS-CoV-2 infection has...
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Treg cell Notch receptors drive SARS-CoV-2-induced MIS-C
In a recent study under consideration at Nature Portfolio Journal and posted to the Research Square* preprint server, researchers demonstrated the evolution of multi-system inflammatory...
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Safety profile of colchicine in COVID-19 patients
In a recent systematic review and meta-analysis published in PLOS ONE, researchers evaluated the use of colchicine in coronavirus disease 2019 (COVID-19) patients. Study: Safety...
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Yale researchers discover immune response pathway that leads to severe COVID-19
Yale researchers have identified a particular immune response pathway that leads to severe illness and death in people infected by the SARS-CoV-2 virus. The study...
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Study investigates biochemical, biophysical, and immunological profile of COVID-19 respiratory secretions
A recent study posted to the medRxiv* preprint server assessed the biophysical, immunological, and biochemical characteristics of respiratory secretions in acute severe acute respiratory syndrome...
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Creation of immunosuppressive environment is key to the progression of colorectal cancer development
Interactions between cells of the immune system and pre-cancerous cells are known to be important contributing factors to the initiation and progression of cancer. However,...
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Developing and manufacturing custom recombinant antibodies for R&D
In this interview, Dr. Linlin Zhang, technical specialist for Sino Biological Europe, discusses how Sino is expanding its product offerings into the European market and...
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Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells
A recent study posted to the Research Square* preprint server and under consideration at Scientific Reports investigated the impact of a recombinant fragment of cellular...
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Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines
In a recent study posted to the bioRxiv* pre-print server, researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1 (CD169), a myeloid cell-specific receptor, in...
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Liposomes tailored for pulmonary delivery for treating acute respiratory distress syndrome
In a recent study published in the Journal of Controlled Release, researchers developed 1,2-dimpalmiyristoyl-sn-glycero-3-phosphocholine (DPPC) liposomes co-loaded with methylprednisolone (MPS) and N-acetyl cysteine (NAC) to...