New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings
Jan 9 2022 A recent study shows how a novel and integrated lab-on-a-chip platform can represent a rapid, affordable, and exact molecular diagnostic tool for...
CRISPR
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Study highlights the usefulness of organoids for basic research into coronaviruses
Researchers from the group of Hans Clevers in collaboration with the group of Bart Haagmans (Erasmus MC) established an organoid biobank to search for the...
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Researchers create an integrated pipeline for performing genetic screening studies
Today’s genetic engineers have a plethora of resources at their disposal: an ever-increasing number of massive datasets available online, highly precise gene editing tools like...
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Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics
In a new study in the journal Accounts of Materials Research, researchers presented an overview of the recent advances in severe acute respiratory syndrome...
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Role of CRISPR-Cas12a visual biosensor in detection of SARS-CoV-2
The current coronavirus disease 2019 (COVID-19) pandemic is caused by the global circulation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is highly...
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The Role of Glycans in the Cell and Glycans Imaging Method
In this interview, News-Medical talks to a pioneer of glycan imaging, Richard Drake about glycans, their role in maintaining cellular homeostasis, glycopeptide analysis, and method...
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Emerging nanomaterials-based biosensor for SARS-CoV-2 detection
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) belongs to the Coronaviridae family. These viruses contain a single non-segmented, single-stranded ribonucleic acid (ssRNA) genome of vertebrates....
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Penn’s newly created split-engineered base editors show potential for research, therapeutics
Targeted mutations to the genome can now be introduced by splitting specific mutator enzymes and then triggering them to reconstitute, according to research from the...
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CRISPR/Cas9 gene editing enables sonodynamic therapy to effectively shrink tumors
Sonodynamic therapy uses ultrasound in combination with drugs to release harmful reactive oxygen species (ROS) at the site of a tumor. However, the treatment isn’t...
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Recent advances in non-viral nano-vector delivery of CRISPR/Cas9 genome editing payloads
In a recent study published in the journal Nano Today, researchers reviewed non-viral nano-vectors used for delivering the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-mediated genome...
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Emerging nanomaterials-based biosensor for detecting SARS-CoV-2
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) belongs to the Coronaviridae family. These viruses contain a single non-segmented, single-stranded ribonucleic acid (ssRNA) genome of vertebrates....
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USP22 crucial for type III interferon signaling and SARS-CoV-2 infection
In a recent study posted to the bioRxiv* pre-print server, a team of researchers demonstrated that ubiquitin-specific peptidase 22 (USP22) is a crucial regulator of...