An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery
A recent review in the Chemical and Pharmaceutical Bulletin looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and...
Macromolecules
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ORF10 protein mutations alter SARS-CoV-2 pathogenicity
The open reading frame 10 (ORF10) protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with multiple human proteins expressed in lung tissues....
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Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting
Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom. They used a technique called...
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Viral biomolecular condensation
Eukaryotic viruses are obligate intracellular parasites in constant coevolution with host cells. Due to containing few protein products and very small genomes, they must rely...
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How cellular clocks regulate cardiac physiology
In this interview, News-Medical speaks to research associate Dr. Alessandra Stangherlin about her latest research that provided new insights into the circadian rhythm of the...
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Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2
The coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a need to develop novel broad-spectrum antivirals that are...